Minimum 10-Year Outcomes of Matrix-Induced Autologous Chondrocyte Implantation in the Knee: A Systematic Review.
Allen S WangChristopher V NagelliAbhinav LambaDaniël B F SarisAaron John KrychMario HevesiPublished in: The American journal of sports medicine (2024)
At a minimum 10-year follow-up, patients undergoing MACI for knee chondral defects demonstrated significant and durable improvements in PROs, satisfactory defect fill on MRI-based assessment, and low rates of reoperation and TKA. These data support the use of MACI as a long-term treatment of focal cartilage defects of the knee.
Keyphrases
- total knee arthroplasty
- patients undergoing
- knee osteoarthritis
- anterior cruciate ligament
- anterior cruciate ligament reconstruction
- magnetic resonance imaging
- high glucose
- type diabetes
- contrast enhanced
- diabetic rats
- metabolic syndrome
- machine learning
- stem cells
- cell therapy
- adipose tissue
- magnetic resonance
- extracellular matrix
- oxidative stress
- diffusion weighted imaging
- mesenchymal stem cells
- drug induced
- soft tissue
- glycemic control