Maternal Cardiac Changes in Women With Obesity and Gestational Diabetes Mellitus.
Sharmaine ThirunavukarasuFaiza AnsariRichard CubbonKaren ForbesChiara Bucciarelli-DucciDavid E NewbyMarc R DweckOliver J RiderLadislav ValkovičChristopher T RodgersDamian J TylerAmrit ChowdharyNicholas JexSindhoora KothaLara MorleyHui XuePeter SwobodaPeter KellmanJohn P GreenwoodSven PleinThomas EverettEleanor ScottTheodoros D KaramitsosPublished in: Diabetes care (2022)
Despite no prior diagnosis of diabetes, women with obesity and GDM manifest impaired myocardial contractility and higher LV mass, associated with reductions in myocardial energetics in late pregnancy compared with lean women with healthy pregnancy. These findings may aid our understanding of the long-term cardiovascular risks associated with GDM.
Keyphrases
- pregnancy outcomes
- type diabetes
- left ventricular
- insulin resistance
- metabolic syndrome
- weight loss
- pregnant women
- high fat diet induced
- preterm birth
- weight gain
- cardiovascular disease
- glycemic control
- heart failure
- human health
- skeletal muscle
- bone mineral density
- atrial fibrillation
- risk assessment
- climate change
- body composition