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Outcomes After Definitive Surgery for Spinal and Sacral Chordoma in 101 Patients Over 20 Years.

Yuanxuan XiaPritika PapaliAbdel-Hameed Al-MistarehiLandon J HansenTej D AzadA Karim AhmedChristian MeyerJohn GrossMajid KhanChetan BettegowdaDebraj MukherjeeTimothy WithamAli BydonNicholas TheodoreJean-Paul WolinskyZiya GokaslanSheng-Fu Larry LoDaniel SciubbaSang H LeeKristin J RedmondDaniel Lubelski
Published in: Neurosurgery (2024)
Surgeons must often weigh the pros and cons of en bloc resection and sacrificing important but affected native tissues. Our findings can provide a benchmark for counseling patients with spinal chordoma. Tumors ≥100 cm3 appear to have a 5.89-times higher risk of recurrence, mobile spine chordomas have a 7.73 times higher risk, and neoadjuvant radiotherapy confers an 11.1 times lower risk for local recurrence. Patients age ≥65 years at surgery have a 16.70 times higher risk of mortality than those <65 years.
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