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Oral Nirmatrelvir and Ritonavir for Covid-19 in Vaccinated, Non-Hospitalized Adults, Ages 18-50 Years.

Jemery Samuel FaustAshish KumarJui ShahSumanth KhadkeSourbha S DaniSarju GanatraPaul E Sax
Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2023)
NMV-r use in vaccinated adults aged 18-50, especially with serious comorbidities, was associated with reduced all-cause hospital visits, hospitalization, and mortality in the first 30 days of Covid-19 illness. However, NMR-r in patients without significant comorbidities or with only asthma/COPD had no association of benefit. Therefore, identifying high-risk patients should be a priority and avoid over-prescription should be avoided.
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