CCR5 receptor antagonism inhibits hepatitis C virus (HCV) replication in vitro.

Jason T BlackardLing KongSusan D RousterRebekah KarnsPaul S HornShyam KottililMohamed Tarek M Shata Kenneth E Sherman

Published in: PloS one (2019)

These data provide evidence that CCR5 modulation could have a significant effect on HCV replication in an in vitro system. Further evaluation of the role of CCR5 inhibition in clinical settings may be warranted.

Keyphrases

hepatitis c virus
human immunodeficiency virus
dendritic cells
regulatory t cells
electronic health record
binding protein
antiretroviral therapy