Two cases of fungal cyst infection in ADPKD: is this really a rare complication?
Luiz Fernando OnuchicVictor Augusto Hamamoto SatoPrecil Diego Miranda de Menezes NevesBruno Eduardo Pedroso BalboAntônio Abel Portela-NetoFernanda Trani FerreiraElieser Hitoshi WatanabeAndreia WatanabeMaria Cláudia Stockler de AlmeidaLeonardo de Abreu TestagrossaPedro Renato ChocairLuiz Fernando OnuchicPublished in: BMC infectious diseases (2019)
Our report highlights the possibility of Candida spp. cyst infection. Failure of clinical improvement with antibiotics should raise the suspicion of a fungal infection. Identification of infected cysts should be pursued in such cases, particularly with PET-CT, and when technically possible followed by cyst aspiration and culture to guide treatment. Risk factors for this condition, such as Candida spp. colonization, previous antimicrobial therapy, hemodialysis, necrotizing pancreatitis, gastrointestinal/hepatobiliary surgical procedure, central venous catheter, total parenteral nutrition, diabetes mellitus and immunodeficiency (neutropenia < 500 neutrophils/mL, hematologic malignancy, chemotherapy, immunosuppressant drugs), should be also considered accepted criteria for empirical antifungal therapy.
Keyphrases
- pet ct
- candida albicans
- chronic kidney disease
- staphylococcus aureus
- biofilm formation
- ultrasound guided
- positron emission tomography
- minimally invasive
- stem cells
- peritoneal dialysis
- end stage renal disease
- mesenchymal stem cells
- locally advanced
- computed tomography
- metabolic syndrome
- radiation therapy
- pseudomonas aeruginosa
- cystic fibrosis
- cell wall