Subanesthetic dose of ketamine for the antidepressant effects and the associated cognitive impairments of electroconvulsive therapy in elderly patients-A randomized, double-blind, controlled clinical study.

Lei ZouSu MinQibin ChenXiao LiLi Ren

Published in: Brain and behavior (2020)

Low-dose ketamine is safe as an adjunct anesthetic for elderly patients subjected to ECT. It has a protective effect on cognitive function and may accelerate the antidepressant effects of ECT.

Keyphrases

low dose
double blind
major depressive disorder
pain management
placebo controlled
clinical trial
high dose
bipolar disorder
study protocol