Implication of Thioredoxin 1 and Glutaredoxin 1 in H2O2-induced Phosphorylation of JNK and p38 MAP Kinases.

Efthymios PouliosVasiliki RoupakaConstantinos GiaginisDimitrios GalarisGiannis Spyrou

Published in: Current molecular medicine (2024)

These results suggest that both Trx1 and Grx1 have protective roles against H2O2 induced toxicity, emphasizing their significance in mitigating oxidative stress-related cellular damage.

Keyphrases

oxidative stress
diabetic rats
high glucose
drug induced
induced apoptosis
signaling pathway
cell death
ischemia reperfusion injury
protein kinase
stress induced
heat shock protein