A higher burden of multiple sclerosis genetic risk confers an earlier onset.

Elina MisickaMary F DavisWoori KimSteven W BruggerJeremy BealesStephanie LoomisPaola G BronsonFarren Basil Shaw Briggs

Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2021)

We demonstrate a significant gradient between elevated MS genetic risk burden and an earlier onset of MS, suggesting that a higher MS genetic risk burden accelerates onset of the disease.

Keyphrases

multiple sclerosis
mass spectrometry
ms ms
genome wide
copy number
white matter
gene expression
breast cancer risk