Opium tincture versus methadone for opioid agonist treatment: a randomized controlled trial.

Mohammadali NikooKiana KianpoorNooshin NikooSanam JavidanbardanAlireza KazemiFiona ChoiMarc VogelAli GholamiSaeed TavakoliJames S H Wong Ehsan Moazen-ZadehReza GivakiMajid JazaniFatemeh MohammadianNader Markazi MoghaddamChristian SchützKerry JangShahin AkhondzadehMichael Krausz

Published in: Addiction (Abingdon, England) (2022)

While this study could not conclude the non-inferiority of opium tincture (OT) to methadone for retaining patients in opioid agonist treatment, OT retained 60% of participants to end of follow-up (85 days) and was superior to methadone in reducing self-reported opioid use outside treatment.

Keyphrases

chronic pain
pain management
newly diagnosed
end stage renal disease
replacement therapy
patient reported outcomes