Miniaturized Microfluidic Electrochemical Biosensors Powered by Enzymatic Biofuel Cell.
Linlin WangWenlei ZhuJianrong ZhangJun-Jie ZhuPublished in: Biosensors (2023)
Electrochemical biosensors, in which enzymatic biofuel cells simultaneously work as energy power and signal generators, have become a research hotspot. They display the merits of power self-support, a simplified structure, in vivo operational feasibility, online and timely monitoring, etc. Since the concept of enzymatic biofuel cell-powered biosensors (EBFC-SPBs) was first proposed, its applications in health monitoring have scored tremendous achievements. However, the creation and practical application of portable EBFC-SPBs are still impeded by the difficulty in their miniaturization. In recent years, the booming microfluidic technology has powerfully pushed forward the progress made in miniaturized and portable EBFC-SPBs. This brief review recalls and summarizes the achievements and progress made in miniaturized EBFC-SPBs. In addition, we also discuss the advantages and challenges that microfluidic and screen-printing technologies provide to wearable and disposable EBFC-SPBs.
Keyphrases
- label free
- single cell
- high throughput
- hydrogen peroxide
- circulating tumor cells
- gold nanoparticles
- cell therapy
- healthcare
- induced apoptosis
- public health
- health information
- social media
- mental health
- molecularly imprinted
- cell proliferation
- heart rate
- blood pressure
- endoplasmic reticulum stress
- mesenchymal stem cells
- cell death
- high resolution
- human health
- health promotion
- simultaneous determination