The reverse remodeling response to sacubitril/valsartan therapy in heart failure with reduced ejection fraction.
Pieter MartensHanne BeliënMatthias DupontPieter VandervoortWilfried MullensPublished in: Cardiovascular therapeutics (2018)
Switching therapy in eligible HFrEF patients from a RAS-blocker to sacubitril/valsartan induces beneficial reverse remodeling of both metrics of systolic as diastolic function.