Serum microRNA‑122 for assessment of acute liver injury in patients with extensive skeletal muscle damage.
Yu ZhangChui Mei OngKara L LynchJavier WaksmanAlan H B WuPublished in: Laboratory medicine (2024)
Recreational drug misuse is associated with both rhabdomyolysis and drug-induced liver injury (DILI). The traditional liver function markers AST and ALT were nonspecifically increased in the majority of patients with ASMI. miR-122 is only increased in patients at risk for DILI and demonstrates superior specificity for liver injury.