Co(II)-Catalyzed Regioselective Pyridine C-H Coupling with Diazoacetates.
Haisheng XieYouxiang ShaoJiao GuiJianyong LanZhipeng LiuZhuo-Feng KeYuanfu DengHuan-Feng JiangWei ZengPublished in: Organic letters (2019)
A Co(II)-catalyzed pyridyl C-H bond carbenoid insertion with α-diazoacetates has been realized. This transformation features a highly regioselective C-C bond formation at the C3-position of pyridines, providing an efficient access to diverse α-aryl-α-pyridylacetates.