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Fibrin Glue Enhances Adipose-Derived Stromal Cell Cytokine Secretion and Survival Conferring Accelerated Diabetic Wound Healing.

Ursula HopfnerMatthias M AitzetmüllerPhilipp NeßbachMichael S HuHans-Guenther MachensZeshaan N MaanDominik Duscher
Published in: Stem cells international (2018)
Although several vehicles have shown to successfully act as cell carrier systems in preclinical trials, regulatory issues have prohibited clinical usage for chronic wounds. By demonstrating the ability of fibrin glue to act as a carrier vehicle for ASCs, while simultaneously enhancing cellular regenerative function and viability, this study is a proponent of clinical translation for ASC-based therapies.
Keyphrases
  • cell therapy
  • wound healing
  • single cell
  • stem cells
  • type diabetes
  • mesenchymal stem cells
  • platelet rich plasma