Clinical and self-reported markers of reproductive function in female survivors of childhood Hodgkin lymphoma.
Katja C E DrechselSimone L BroerFrancis StoutjesdijkJos W R TwiskMarleen H van den BergCornelis Nils LambalkFlora E van LeeuwenA OverbeekMarry M M van den Heuvel-EibrinkW van DorpAndrica De VriesJacqueline J LoonenHelena J H Van der PalLeontien C M KremerWim J E TissingA Birgitta VersluysGertjan J L KaspersEline Van Dulmen-den BroederMargreet A Veeningnull nullPublished in: Journal of cancer research and clinical oncology (2023)
HL survivors appear to have an impaired ovarian reserve. However, chance to achieve pregnancy seems reassuring at a young age. Additional follow-up studies are needed to assess fertile life span and reproductive potential of HL survivors, in particular for current HL treatments that are hypothesized to be less gonadotoxic.