Parent Quality of Life After Disclosure of Pediatric Oncology Germline Sequencing Results.
Katianne M Howard SharpChen LiZhao-Hua LuMary Egan ClarkNiki JurbergsAnnastasia OumaLynn HarrisonElsie GerhardtLeslie TaylorKayla V HamiltonRose B McGeeRegina NuccioStacy J Hines-DowellJami S GattusoMichelle PritchardBelinda N MandrellKenneth P TercyakKim E NicholsLiza-Marie Marie JohnsonPublished in: JCO precision oncology (2023)
Germline genomic sequencing for children with cancer is associated with distress among parents when revealing an underlying cancer predisposition among their affected children. Genetic education and counseling before and after germline sequencing may help attenuate this impact on QoL by addressing parents' concerns about test results and their health implications. Assessing parents' worry early in the testing process may also aid in identifying those most likely in need of psychosocial support.