Intact NOX2 in T Cells Mediates Pregnancy-Induced Renal Damage in Dahl SS Rats.

John Henry DasingerJustine M Abais-BattadSamuel D WaltonEmily C Burns-RayMary Cherian-ShawKaitlyn E BaldwinDaniel J Fehrenbach David L Mattson

Published in: Hypertension (Dallas, Tex. : 1979) (2024)

T cells and NOX2-derived reactive oxygen species, thus, contribute to end-organ damage in both primigravida and multigravida pregnancies in the SS rat leading to increases in maternal mortality.

Keyphrases

reactive oxygen species
pregnancy outcomes
oxidative stress
diabetic rats
preterm birth
high glucose
pregnant women
gestational age
birth weight
risk factors
drug induced
type diabetes
coronary artery disease
cardiovascular disease