Evaluation of maternal serum vascular endothelial growth factor C and D levels in intrahepatic cholestasis of pregnancy.

Nihat FarisoğullarıAtakan TanaçanBedri SakcakRamazan DenizliEzgi BaşaranÖzgür KaraNuray YazihanDilek Şahin

Published in: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics (2023)

This study showed that the maternal serum VEGF-C level was higher and the VEGF-D level was lower in patients with ICP compared with healthy pregnant women. We also found that the VEGF-C level was correlated with the serum bile acid level in patients with severe ICP. Serum VEGF-C level can be used in the diagnosis and follow-up of intrahepatic pregnancy cholestasis.

Keyphrases

vascular endothelial growth factor
endothelial cells
pregnant women
pregnancy outcomes
preterm birth
drug induced
early onset
birth weight
physical activity