Blood biomarkers for cardiac damage during and after radiotherapy for esophageal cancer: A prospective cohort study.

Jannet C BeukemaJan-Willem HavemanJohannes A LangendijkEdwin OldehinkelAlphons C M van den BerghJacco J de HaanJoost P van MellePeter van LuijkChristina T Muijs

Published in: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology (2024)

Significant correlations were found for both biomarkers with radiation dose and clinical toxicity endpoints after treatment. Therefore, these markers might be of additional value in NTCP models for cardiac events and might help us unravelling the mechanisms behind these toxicity endpoints.

Keyphrases

oxidative stress
left ventricular
early stage
radiation therapy
locally advanced
radiation induced
heart failure
squamous cell carcinoma
oxide nanoparticles
atrial fibrillation
rectal cancer