The Complex Latent Structure of Attenuated Psychotic Symptoms: Hierarchical and Bifactor Models of SIPS Symptoms Replicated in Two Large Samples at Clinical High Risk for Psychosis.
Henry R CowanTrevor F WilliamsVijay Anand MittalJean AddingtonCarrie E BeardenKristin S CadenheadTyrone D CannonBarbara A CornblattMatcheri KeshevanDiana O PerkinsDaniel H MathalonWilliam S StoneScott W WoodsElaine F WalkerPublished in: Schizophrenia bulletin (2024)
Attenuated psychotic symptoms, measured by the SIPS, have a complex hierarchical structure with a strong general factor. The general factor relates to internalizing symptoms and functional impairment, emphasizing the roles of general psychopathological distress/impairment in psychosis risk. Shared symptom variance complicates the interpretation of raw symptom scores. Broad transdiagnostic assessment is warranted to model psychosis risk accurately.