Microwave-assisted one pot three-component synthesis of some novel pyrazole scaffolds as potent anticancer agents.

Sobhi Mohamed GomhaMastoura M EdreesRasha A M FatyZeinab A MuhammadYahia N Mabkhot

Published in: Chemistry Central journal (2017)

All the newly synthesized compounds were evaluated for their anticancer activity against human lung cancer and human hepatocellular carcinoma cell lines using MTT assay. The results obtained exploring the high potency of six of the tested compounds compared with cisplatin. Graphical abstract Microwave-assisted one pot three-component synthesis of some novel pyrazole scaffolds as potent anticancer agents.

Keyphrases

endothelial cells
molecular docking
induced pluripotent stem cells
tissue engineering
high throughput