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Decreased integration of the frontoparietal network during a working memory task in major depressive disorder.

Wenjian TanZhening LiuChang XiMengjie DengYicheng LongLena PalaniyappanJie Yang
Published in: The Australian and New Zealand journal of psychiatry (2020)
We report a putative mechanistic link between the global efficiency of the frontoparietal network and impaired n-back performance in major depressive disorder. This relationship is more pronounced at lower levels of symptom burden, indicating the possibility of multiple pathways to cognitive deficits in severe major depressive disorder.
Keyphrases
  • major depressive disorder
  • working memory
  • bipolar disorder
  • transcranial direct current stimulation
  • attention deficit hyperactivity disorder