Formulae recently proposed to estimate renal glomerular filtration rate improve the prediction of carboplatin clearance.

Melanie White-KoningMarie Noëlle PaludettoFélicien Le LouedecLaurence GladieffChristine ChevreauEtienne ChatelutFlorent Puisset

Published in: Cancer chemotherapy and pharmacology (2020)

Whereas CysC improves carboplatin CL prediction, the Calvert-CKD-EPI equation seems the most suitable creatinine-based formula to predict carboCL homogeneously in all subgroups of patients.

Keyphrases

end stage renal disease
chronic kidney disease
ejection fraction
newly diagnosed
phase ii study
clinical trial
radiation therapy
human milk
preterm infants
phase iii