18F-PSMA-1007 multiparametric, dynamic PET/CT in biochemical relapse and progression of prostate cancer.

Christos SachpekidisA Afshar-OromiehK KopkaD S StraussL PanU HaberkornA Dimitrakopoulou-Strauss

Published in: European journal of nuclear medicine and molecular imaging (2019)

18F-PSMA-1007 PET/CT could detect PC lesions in 60% of the patients of a mixed population, including also patients with very low PSA values. Higher PSA values were associated with a higher detection rate. Dynamic PET analysis revealed an increasing tracer uptake during the dynamic PET acquisition as well as high binding and internalization of the radiofluorinated PSMA ligand in the PC lesions.

Keyphrases

pet ct
prostate cancer
positron emission tomography
radical prostatectomy
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
peritoneal dialysis
prognostic factors
computed tomography
single cell
quantum dots
patient reported
free survival