Epithelial Barrier Dysfunction in Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D) via Downregulation of Claudin-1.
Karem AwadChristian BarmeyerChristian BojarskiOliver NagelIn-Fah M LeeMichal R SchweigerJörg-Dieter SchulzkeRoland BückerPublished in: Cells (2023)
Barrier dysfunction as a result of epithelial tight junction changes plays a role in IBS-D as a pathomechanism inducing a leak flux type of diarrhea.