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Tumor cell PD-L1 expression is a strong predictor of unfavorable prognosis in immune checkpoint therapy-naive clear cell renal cell cancer.

Katharina MöllerChristoph FrauneNiclas C BlessinMaximilian LennartzMartina KluthClaudia Hube-MaggLinnea LindhorstRoland DahlemMargit FischTill EichenauerSilke RiechardtRonald SimonGuido SauterFranziska BüscheckWolfgang HöppnerCord MatthiesOusman DohTill KrechAndreas H MarxHenrik ZechaMichael RinkStefan SteurerTill S Clauditz
Published in: International urology and nephrology (2021)
These data suggest that PD-L1 expression in highly immunogenic RCCs facilitates immune evasion and contributes to cancer aggressiveness.
Keyphrases
  • papillary thyroid
  • single cell
  • cell therapy
  • squamous cell
  • clear cell
  • stem cells
  • hiv infected
  • squamous cell carcinoma
  • bone marrow
  • childhood cancer
  • young adults
  • data analysis