Interleukin-21: a potential biomarker for diagnosis and predicting prognosis in COVID-19 patients

Nilüfer Aylin Acet Öztürk Ahmet Ursavaş Aslı Görek Dilektaşlı Ezgi Demirdöğen Çetinoğlu Necmiye Funda Coşkun Dane Ediger Ayşe Esra Uzaslan Digdem Y Ermis Mert Karaca Orkun Eray Terzi Merve Bayram Dilara Ömer Topçu Büşra Yiğitliler Ahmet Yurttaş Shahriyar Maharramov Gamze Yazici Haluk Barbaros Oral Mehmet Karadağ

Published in: Turkish journal of medical sciences (2021)

We identified specific differences in serum IL-21 between COVID-19 and non-COVID-19 pneumonia patients. Serum IL-21 measurement has promising predictive value for disease progression in COVID-19 patients. High serum IL-6 and IL-21 levels obtained upon admission are independent risk factors for clinical worsening.

Keyphrases

sars cov
coronavirus disease
end stage renal disease
chronic kidney disease
respiratory syndrome coronavirus
prognostic factors
intensive care unit
patient reported outcomes
acute respiratory distress syndrome
patient reported