Comparative Evaluation of GeneXpert MTB/RIF Ultra and GeneXpert MTB/RIF for Detecting Tuberculosis and Identifying Rifampicin Resistance in Pars Plana Vitrectomy Samples of Patients with Ocular Tuberculosis.

Kusum SharmaMegha SharmaNikitha AyyaduraiMohit DograAman SharmaVishali GuptaRamandeep SinghAmod Gupta

Published in: Ocular immunology and inflammation (2022)

OTB: Ocular tuberculosis; Ultra: Xpert MTB/RIF Ultra; Xpert: Xpert MTB/RIF, MPCR: multiplex polymerase chain reaction; NAATs: Nucleic acid amplification tests; MLAMP: multitargeted loop-mediated isothermal amplification; PPV: positive predictive value; NPV: negative predictive value; EPTB: extrapulmonary tuberculosis; VF: vitreous fluid; DNA: deoxyribonucleic acid; ATT: antitubercular therapy; RifR: Rifampicin resistance; RifS: Rifampicin susceptible; RifI: Rifampicin indeterminate.

Keyphrases

pulmonary tuberculosis
mycobacterium tuberculosis
nucleic acid
high resolution
loop mediated isothermal amplification
emergency department
high throughput
single molecule
sensitive detection
cell free
optical coherence tomography