Cannabinoid CB1 /CB2 receptor agonists attenuate hyperactivity and body weight loss in a rat model of activity-based anorexia.
Maria SchermaValentina SattaRoberto ColluMaria Francesca BoiPaolo UsaiWalter FrattaPaola FaddaPublished in: British journal of pharmacology (2017)
Taken together, our results further demonstrate the involvement of the EC system in AN pathophysiology and that strategies which modulate EC signalling are useful to treat this disorder, specifically in patients where physical hyperactivity plays a central role in its progression and maintenance.