Sleep-related breathing disorder in non-infectious pulmonary complications after pediatric allogeneic stem cell transplantation.
Elli-Maija UkonmaanahoTurkka KirjavainenLaura MarteliusJouko LohiRiitta KarikoskiMinna KoskenvuoMervi TaskinenPublished in: Pediatric research (2022)
Children with severe obstructive lung function and chronic lung graft-versus-host disease following hematopoietic stem cell transplantation are more likely to present with sleep-related mild hypoxia and hypoventilation than children with restrictive lung disease. To our knowledge there are no reports on sleep-related breathing disorders and ventilatory function measured by polysomnography in children with pulmonary complications after allogeneic HSCT. Polysomnography may add to the differential diagnostics between patients with BOS and other non-infectious pulmonary complications.
Keyphrases
- stem cell transplantation
- lung function
- high dose
- pulmonary hypertension
- young adults
- obstructive sleep apnea
- sleep quality
- physical activity
- bone marrow
- cystic fibrosis
- chronic obstructive pulmonary disease
- air pollution
- hematopoietic stem cell
- sleep apnea
- risk factors
- depressive symptoms
- low dose
- electronic health record