Sequence analysis and variant identification at the APOC3 gene locus indicates association of rs5218 with BMI in a sample of Kuwaiti's.

Zainab H MalallaAhmad E Al-SerriHuda M AlAskarWafaa Y Al-KandariSuzanne A Al-Bustan

Published in: Lipids in health and disease (2019)

The present study is the first to report sequence analysis of APOC3 in an Arab ethnic group. This study supports the inclusion of rs5128 as a marker for assessing genetic risk to dyslipidemia and obesity and the inclusion of the novel variant g.5196 A > G for population stratification of Arabs.

Keyphrases

type diabetes
metabolic syndrome
copy number
insulin resistance
body mass index
weight loss
gene expression
amino acid
genome wide identification