Contribution of upregulated aminoacyl-tRNA biosynthesis to metabolic dysregulation in gastric cancer.

Xiaoling Gao Rui Guo Yonghong Li Guolan Kang Yu Wu Jia Cheng Jing Jia Wanxia Wang Zhenhao Li Anqi Wang Hui Xu Yanjuan Jia Yuanting Li Xiaoming Qi Zhenhong Wei Chaojun Wei

Published in: Journal of gastroenterology and hepatology (2021)

This study demonstrated that the aminoacyl-tRNA biosynthesis pathway is upregulated in gastric cancer and both TARS and FARSB play key roles in the progression of gastric cancer. Additionally, a novel therapeutic strategy for gastric cancer was proposed that involves targeting the aminoacyl-tRNA biosynthesis pathway.

Keyphrases

cell wall
cancer therapy