The first reports of FA2H-associated neurodegeneration from two unrelated Iranian families.
Narges HashemiReza Nejad Shahrokh AbadiAfagh AlaviMohammad RohaniAida GhasemiAli Reza TavasoliPublished in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2023)
FAHN is an uncommon variant of NBIA that may manifest as spastic paraparesis without signs of iron buildup on brain imaging. As a result, it should be taken into account while making a differential diagnosis of the hereditary spastic paraplegia (HSP) syndrome, especially in individuals who lack iron deposits.