Endothelial response to type I interferon contributes to vasculopathy and fibrosis and predicts disease progression of systemic sclerosis.
Hanlin YinAnastasiia KozlovaLichong ShenXiaojiang XuYe YuanRui LiBei LiuQianqian LiQianru HuangFeng XieZhiliang ZhangRui LiangXueyu DaiXiaoxiang ChenBin LiQingran YanLiangjing LuPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2023)
The EC IFN-1 signature distinguished SSc skin subtypes and disease progression and may contribute to vasculopathy and fibrosis.