NHC-Zn alkyl catalyzed cross-dehydrocoupling of amines and silanes.
Adimulam HarinathHimadri KarmakarDevadkar Ajitaro KisanHari Pada NayekTarun K PandaPublished in: Organic & biomolecular chemistry (2023)
An N -heterocyclic carbene-zinc alkyl complex [Im Dipp Zn(CH 2 CH 3 ) 2 ] (Im = imidazol-2-ylidene and Dipp = 2,6-diisopropylphenyl) acts as a catalyst in the cross-dehydrogenative coupling (CDC) of a wide range of primary and secondary amines and hydrosilanes to yield a substantial quantity of the corresponding aminosilanes with good chemoselectivity at room temperature. A broad substrate scope was observed during the zinc-catalyzed CDC reaction. Two zinc complexes, [{Im Mes Zn( μ -NHPh)(NHPh)} 2 ] (Mes = mesityl) (3) and [{Im Dipp Zn(CH 2 CH 3 )( μ -H)} 2 ] (4), were isolated and structurally characterized as intermediates through controlled reactions to ascertain the CDC mechanism.