Exosomal microRNA-223 from neutrophil-like cells inhibits osteogenic differentiation of PDLSCs through the cGMP-PKG signaling pathway.

Zheng ZhangPengcheng WangYouli ZhengMinghui WangJiashu ChouZuomin Wang

Published in: Journal of periodontal research (2023)

Our findings suggest that neutrophil-like cells derived exosomes might inhibit osteogenic differentiation of PDLSCs by transporting miR-223 and regulating the cGMP-PKG signaling pathway.

Keyphrases

signaling pathway
pi k akt
nitric oxide
cell proliferation
epithelial mesenchymal transition
protein kinase
long non coding rna
induced apoptosis
mesenchymal stem cells
stem cells
bone marrow