Identification of a Notch transcriptomic signature for breast cancer.
Eike-Benjamin BrauneFelix GeistXiaojia TangKrishna KalariJudy BougheyLiewei WangRoberto A Leon-FerreAntonino B D'AssoroJames N IngleMatthew P GoetzJulian KreisKang WangTheodoros FoukakisAnita SeshireDirk WienkeUrban LendahlPublished in: Breast cancer research : BCR (2024)
The 20-gene transcriptional signature will be a valuable tool to evaluate the response of future Notch-targeting therapies for breast cancer, to learn about potential effects on Notch signalling from conventional breast cancer therapies and to better stratify patients for therapy considerations.
Keyphrases
- cell proliferation
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- gene expression
- transcription factor
- patient reported outcomes
- genome wide
- cancer therapy
- drug delivery
- mesenchymal stem cells
- current status
- climate change
- dna methylation
- rna seq
- bone marrow
- smoking cessation
- genome wide analysis