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Exploring promising minor natural phenolic compounds in neuroprotection-related preclinical models.

Carlos Franciney Moreira VasconcelosAgnieszka Zofia NeugebauerRicardo Basto Souza
Published in: Basic & clinical pharmacology & toxicology (2024)
Neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, are characterised by the progressive loss of specific neuronal cell populations due to multifactorial factors, including neurochemical and immunological disturbances. Consequently, patients can develop cognitive, motor and behavioural dysfunctions, which lead to impairments in their quality of life. Over the years, studies have reported on the neuroprotective properties inherent in phenolic compounds. Therefore, this review highlights the most recent scientific findings regarding phenolic compounds as promising neuroprotective molecules against neurodegenerative diseases.
Keyphrases
  • cerebral ischemia
  • end stage renal disease
  • newly diagnosed
  • ejection fraction
  • cell therapy
  • chronic kidney disease
  • multiple sclerosis
  • subarachnoid hemorrhage
  • cognitive decline
  • patient reported outcomes