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Neurogenesis in neurodegenerative diseases in the adult human brain.

Tomasz Stępień
Published in: Postepy psychiatrii neurologii (2021)
Restoring the balance between dying and emerging neurons is important and offers hope for new therapy directions in the treatment of neurodegenerative diseases. We note common points that could become the target of further research. Attention should be paid to disorders of the calcium metabolism, so important in signal transduction, the state of mitochondria with enzymes involved in the formation of ATP, and the reduction of inflammation in neurogenic regions.
Keyphrases
  • oxidative stress
  • spinal cord injury
  • palliative care
  • spinal cord
  • working memory
  • cell death
  • reactive oxygen species
  • combination therapy
  • stem cells
  • mesenchymal stem cells
  • cerebral ischemia
  • bone marrow