Clinical predictors of working memory performance in obstructive sleep apnea patients before and during extended wakefulness.
David James StevensAngela L D'RozarioHannah OpenshawDelwyn BartlettCaroline D RaePeter G CatchesideKeith K H WongR Doug McEvoyRonald R GrunsteinAndrew VakulinPublished in: Sleep (2022)
O2 nadir, age, and sleepiness show prognostic value for predicting WM impairment in both rested and sleep-deprived OSA patients and may guide clinicians in identifying patients most at risk of impaired WM under both rested and heightened sleep pressure conditions.Clinical Trial Registration: This manuscript presents data collected as part of a larger trial-ANZCTR: Novel brain biomarkers of performance impairment in sleep apnea-https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=363830, No. ACTRN12613001171707.
Keyphrases
- obstructive sleep apnea
- end stage renal disease
- clinical trial
- working memory
- newly diagnosed
- ejection fraction
- chronic kidney disease
- positive airway pressure
- prognostic factors
- physical activity
- phase ii
- patient reported outcomes
- sleep quality
- depressive symptoms
- electronic health record
- resting state
- artificial intelligence
- white matter
- attention deficit hyperactivity disorder
- sensitive detection
- deep learning
- double blind