Higher testosterone is associated with open-angle glaucoma in women: a genetic predisposition?

Joëlle E VergroesenAdem KaynakElif AribasMaryam KavousiJoyce B J van MeursCaroline C W KlaverWishal D Ramdas

Published in: Biology of sex differences (2023)

In women, higher testosterone levels increased the risk of iOAG. Both IOP-dependent and IOP-independent mechanisms may underlie this association. Managing testosterone levels may be particularly relevant for the prevention of neurodegeneration in the eye. Future research should confirm these findings.

Keyphrases

replacement therapy
polycystic ovary syndrome
pregnancy outcomes
cervical cancer screening
type diabetes
copy number
gene expression
dna methylation
adipose tissue