Concomitant continuous pain in patients with trigeminal neuralgia is associated with trigeminal nerve root atrophy.
Giulia Di StefanoGianfranco De StefanoCaterina LeoneGiorgio CruccuStefano TardioliGaia CartocciMarco FiorelliAndrea TruiniFrancesca CaramiaPublished in: Cephalalgia : an international journal of headache (2020)
Our clinical and neuroimaging study found that in patients with trigeminal neuralgia, concomitant continuous pain was associated with trigeminal nerve root atrophy, therefore suggesting that this type of pain is likely related to axonal loss and abnormal activity in denervated trigeminal second-order neurons.