Combined therapy of photobiomodulation and adipose-derived stem cells synergistically improve healing in an ischemic, infected and delayed healing wound model in rats with type 1 diabetes mellitus.
Roohollah Ebrahimpour-MalekshahAbdollah AminiFatemeh ZareAtarodsadat MostafaviniaSamin DavoodyNiloofar DeraviMohammad RahmanianSeyed Mahmoud HashemiMalihe HabibiSeyed Kamran GhoreishiSufan ChienSasha ShafikhaniHoussein AhmadiSahar BayatMohammad BayatPublished in: BMJ open diabetes research & care (2021)
Combination therapy of PBM+ADS is more effective that either PBM or ADS in stimulating skin injury repair, and modulating inflammatory response in an MRSA-infected wound model of rats with DM1.
Keyphrases
- wound healing
- combination therapy
- inflammatory response
- staphylococcus aureus
- methicillin resistant staphylococcus aureus
- signaling pathway
- stem cells
- lipopolysaccharide induced
- surgical site infection
- type diabetes
- metabolic syndrome
- ischemia reperfusion injury
- immune response
- adipose tissue
- mesenchymal stem cells
- oxidative stress
- skeletal muscle
- replacement therapy