Intrinsic Molecular Subtypes of Metastatic Castration-Resistant Prostate Cancer.
Eric FengNicholas R RydzewskiMeng ZhangArian LundbergMatthew L BootsmaKyle T HelzerJoshua M LangRahul R AggarwalEric J SmallDavid A QuigleyMartin SjostromShuang G ZhaoPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Our results emphasize the heterogeneity of mCRPC beyond currently accepted molecular phenotypes, and suggests that future studies should consider incorporating transcriptome-wide profiling in order to better understand how these differences impact treatment responses and outcomes.