Subchronic administration of scopolamine reverses UCMS-induced behavior in mice via eEF2 protein dephosphorylation.

Yana Babii Agnieszka Pałucha-Poniewiera Anna Rafało-Ulińska Piotr Brański Andrzej Pilc

Published in: Pharmacological reports : PR (2024)

Subchronic administration of scopolamine is needed to ameliorate UCMS-induced depressive-like behavior. The suggested mechanism of scopolamine action covers eEF2 protein activity in the PFC.

Keyphrases

high glucose
diabetic rats
drug induced
oxidative stress
binding protein
endothelial cells
metabolic syndrome
high fat diet induced
insulin resistance