Role of S1P/S1PR3 axis in release of CCL20 from human bronchial epithelial cells.

Yoshitaka KawaTatsuya NaganoAsuka YoshizakiRyota DokuniMasahiro KatsuradaTomomi TerashitaYuichiro YasudaKanoko UmezawaMasatsugu YamamotoHiroshi KamiryoKazuyuki KobayashiYoshihiro Nishimura

Published in: PloS one (2018)

S1P/S1PR3 pathways have a role in release of proinflammatory cytokines from bronchial epithelial cells. Our results suggest that S1P/S1PR3 may be a possible candidate for the treatment of bronchial asthma.

Keyphrases

endothelial cells
chronic obstructive pulmonary disease
lung function
combination therapy