Flow-splitting-based computation of outlet boundary conditions for improved cerebrovascular simulation in multiple intracranial aneurysms.

The results reveal that outlet boundary conditions have a crucial impact on image-based blood flow simulations, especially for multiple aneurysm studies. We could confirm the advantages of the more complex outflow-splitting model (4) including an incremental improvement (5) compared to strategies (1), (2) and (3) for this application scenario. Furthermore, we discourage from using zero-pressure configurations that lack a physiological basis.