Trends in Cases, Hospitalization and Mortality Related to the Omicron BA.4/BA.5 Sub-Variants in South Africa.

Waasila JassatSalim S Abdool KarimLovelyn OzougwuRichard WelchCaroline MudaraMaureen MashaPetro RousseauMilani WolmaransAnthony SelikowNevashan GovenderSibongile WalazaAnne von GottbergNicole WolterPedro Terrence PisaIan SanneSharlene GovenderOyewale TomoriCheryl CohenMichelle J Groomenull null

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)

Overall, admission incidence risk and in-hospital mortality, which had increased progressively in South Africa's first three waves, decreased in the fourth Omicron BA.1/BA.2 wave and declined even further in the fifth Omicron BA.4/BA.5 wave. Mortality risk was lower in those with natural infection and vaccination, declining further as the number of vaccine doses increased.

Keyphrases

south africa
risk factors
emergency department
gene expression
copy number
dna methylation
human immunodeficiency virus
genome wide