Tetramethylpyrazine alleviates hypoxia-induced proliferation, migration, and inflammatory response of fibroblast-like synoviocytes via inhibiting the HIF-1α- circCDC42BPB pathway.
Yu-Jing ZhangLi-Feng ChenXu LiJian-Hua ChenZhang-Kui TanPublished in: Advances in rheumatology (London, England) (2024)
TMP might block RA-FLS injury partly via regulating the HIF-1α- circCDC42BPB pathway, providing a promising therapeutic target for RA.